Itraconazole – What It Is and When Doctors Prescribe It
If you’ve been told to take itraconazole, you’re likely dealing with a fungal infection that needs more than an over‑the‑counter cream. Itraconazole is a prescription antifungal that works by stopping the fungus from building its cell wall, which kills or stops its growth. Doctors commonly use it for conditions like blastomycosis, histoplasmosis, aspergillosis, and certain nail infections.
How to Take Itraconazole Correctly
The drug comes as capsules or a liquid solution. For the capsule form, swallow it whole with a full glass of water – don’t crush or split it. Food matters: most doctors recommend taking itraconazole with a meal that has some fat because it helps your body absorb the medicine better.
Dosage varies by infection. A typical nail‑fungus course might be 200 mg once daily for several weeks, while lung infections can need 100–400 mg per day split into two doses. Always follow the schedule your doctor gave you; missing days can let the fungus bounce back.
Because itraconazole stays in your system for a while, don’t start a new dose before finishing the prescribed course unless your doctor says otherwise. If you forget a dose, take it as soon as you remember – but if it’s almost time for the next one, skip the missed pill and keep to the regular timing.
Common Side Effects & When to Call a Doctor
Most people feel fine, but some notice mild stomach upset, nausea, or headache. These usually fade after a few days. More serious signs include dark urine, yellowing skin or eyes (a sign of liver trouble), severe abdominal pain, or swelling in your legs.
If you experience any of those, contact your doctor right away. Itraconazole can affect liver enzymes, so doctors often order blood tests before starting treatment and periodically during therapy to make sure the liver is handling the drug.
Another important safety note: itraconazole interacts with several common meds, especially statins (like simvastatin), some anti‑arrhythmics, and certain antibiotics. Mixing them can raise the risk of muscle damage or heart rhythm problems. Always hand your pharmacist a complete list of what you’re taking – even over‑the‑counter supplements.
Pregnant or nursing mothers should avoid itraconazole unless the benefits far outweigh the risks, as animal studies suggest potential harm to a developing baby. If you’re planning to become pregnant, discuss alternatives with your doctor first.
Storing the medication is simple: keep capsules in a dry place at room temperature, and if you have the liquid form, store it in the refrigerator after opening. Keep it out of reach of children.
In summary, itraconazole can clear stubborn fungal infections when used correctly. Take it with food, stick to your schedule, watch for side effects, and stay on top of any drug interactions. If you’re unsure about anything – dosage, missed pills, or a new symptom – reach out to your healthcare provider. They’ll help you finish the treatment safely and get back to feeling normal.

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