Bilastine and Drug Interactions: What You Should Be Aware Of

Apr, 27 2023

Introduction to Bilastine and Its Uses

Bilastine is a second-generation antihistamine that has gained popularity in recent years for its effectiveness in treating allergic symptoms such as sneezing, itching, runny nose, and watery eyes. It's commonly used in the treatment of allergic rhinitis and urticaria, providing relief to millions of people worldwide. However, as with any medication, it's essential to be aware of potential drug interactions and how they may impact the effectiveness or safety of bilastine. In this article, we'll explore some common drug interactions and provide advice on what precautions to take when using bilastine.

The Importance of Understanding Drug Interactions

Drug interactions occur when one medication affects the way another medication works, either by increasing or decreasing its effectiveness, or causing side effects. This can lead to unexpected health complications or even life-threatening situations. Therefore, understanding possible drug interactions with bilastine is crucial for ensuring that you receive the best possible care and prevent any unwanted side effects.

Common Drug Interactions with Bilastine

While bilastine has been shown to have a low potential for drug interactions, there are still a few medications that may interact with it. Some of these include:

Central Nervous System Depressants

Combining bilastine with other central nervous system (CNS) depressants like alcohol, benzodiazepines, or opioids may increase drowsiness and impair cognitive function. It's essential to avoid or limit the use of these substances while taking bilastine to prevent excessive sedation or other adverse effects.

Antifungal and Antibacterial Medications

Certain antifungal and antibacterial medications, such as ketoconazole and erythromycin, may increase the concentration of bilastine in the blood, potentially leading to an increased risk of side effects. If you need to take one of these medications, make sure to discuss it with your healthcare provider to determine the best course of action.

Over-the-Counter Medications and Supplements

It's not just prescription medications that can interact with bilastine; over-the-counter (OTC) medications and dietary supplements can also cause interactions. Some common OTC medications to be aware of include:


Antacids containing aluminum or magnesium hydroxide can reduce the absorption of bilastine, decreasing its effectiveness. It's recommended to take bilastine at least one hour before or two hours after taking an antacid to avoid this interaction.

Herbal Supplements

Certain herbal supplements, such as St. John's wort, may also interact with bilastine. If you're currently taking any herbal supplements, it's essential to discuss them with your healthcare provider to determine if any potential interactions exist.

How to Minimize the Risk of Drug Interactions

There are several steps you can take to minimize the risk of drug interactions while taking bilastine. These include:

  • Informing your healthcare provider of all medications and supplements you're currently taking
  • Always reading the labels of OTC medications and supplements to check for potential interactions
  • Following your healthcare provider's advice on when and how to take your medications
  • Being cautious when combining bilastine with other CNS depressants and avoiding excessive alcohol consumption

Monitoring for Potential Side Effects and Interactions

While taking bilastine, it's essential to monitor for potential side effects or signs of drug interactions. If you notice any unusual symptoms or worsening of your allergic symptoms, contact your healthcare provider immediately. They can help determine if a drug interaction is occurring and advise you on the best course of action.

Conclusion: Staying Safe and Informed

Overall, being aware of potential drug interactions with bilastine is crucial for ensuring you receive the best possible care and avoid any unwanted side effects. By following the advice outlined in this article, you can minimize the risk of drug interactions and enjoy the benefits of bilastine in treating your allergic symptoms safely and effectively.